ADVERTISEMENT
Fluvoxamine is an inexpensive anti-depressant commonly used in mental healthcare. Evidence from the recently concluded clinical trial suggest that it can be repurposed to treat patients with COVID-19. It is found to reduce risk of severe COVID-19 symptoms, reduces need...
Anti-viral properties of manuka honey are due to the presence of methylglyoxal (MG), an arginine directed glycating agent that modifies sites specifically present in the SARS-CoV-2 genome, thereby interfering with its replication and inhibiting the virus. In addition, manuka...
A type of virus that preys on bacteria could be harnessed to combat bacterial infections in patients whose immune systems have been weakened by the SARS-CoV-2 virus that causes the COVID-19 disease, according to an expert at the University...
The plant derived agent, Thapsigargin (TG) has been used in traditional medicine for long time. TG has shown promises as a potential anti-cancer drug because of its biological property to inhibit the sarcoplasmic/endoplasmic reticulum Ca2+ ATPase (SERCA) pump which is necessary for...
Coronaviruses are RNA viruses belonging to coronaviridae family. These viruses display remarkably high rates of errors during replication due to lack of proofreading nuclease activity of their polymerases. In other organisms, the replication errors are corrected but the coronaviruses lack this ability. As...
A recent study suggests increased risk of formation of coronavirus hotspots caused due to deforestation and livestock revolution leading to zoonotic transmission of coronavirus from bats to humans. The study seems to sow enough subliminal seeds in the minds...
Deltacron is not a new strain or variant but a case of co-infection with two variants of SARS-CoV-2. Over the past two years, different variants have emerged of the SARS CoV-2 strain with varying degree of infectivity and disease...
For quicker lifting of lockdown, the innovators or entrepreneurs holding IP rights over novel technologies with potential to improve diagnostics and therapeutics for COVID-19, who may otherwise be unable to launch the products at scaled up level due to...
Herd immunity for COVID-19 is said to be achieved when 67% of the population is immune to the virus through infection and/or vaccination, whilst the pathogen remains well-characterized (unmutated) throughout transmission in the population that is well-characterized. In the...
Effective 27th January 2022, it will not be mandatory to wear a face covering or need to show COVID pass in England. The measures put in place under Plan B in England, to be lifted.   Earlier on 8th December...
A combination of biological and computational approach to study protein-protein interactions (PPIs) between the viral and the host proteins in order to identify and repurpose drugs for an effective treatment of COVID-19 and possibly other infections as well The usual...
Single dose of the vaccine can increase vaccine coverage rapidly which is an imperative in many countries where level of vaccine uptake is not optimal.   WHO has updated its interim recommendations1 on the use of the Janssen Ad26.COV2.S (COVID-19). One-dose schedule of...
A new variant called ‘IHU’ (a new Pangolin lineage named B.1.640.2) is reported to have emerged in south-eastern France.   Researchers in Marseille, France have reported detection of a new variant of novel coronavirus SARS-CoV-2.   The index patient had recent travel history...
2-Deoxy-D-Glucose(2-DG), a glucose analog that inhibits glycolysis, has recently received Emergency Use Authorization (EUA) in India for the treatment of moderate to severe COVID-19 patients. The molecule has been extensively researched and used in clinical trials for its ant-cancer properties....
Several new strains of the virus have emerged since the pandemic began. New variants were reported as early as February 2020. The current variant that has brought the UK to standstill this Christmas is said to be 70% more...
The preliminary report of findings from the clinical trial NCT02735707 reported in preprint suggests that Tocilizumab and Sarilumab, the interleukin-6 receptor antagonists are effective in treating critically ill COVID-19 patients and improve survival. Severely ill COVID-19 patients receiving intensive care support responded well to...
Convalescent plasma therapy holds key for the immediate treatment of severely sick COVID-19 patients. This article discusses effectiveness of this therapy and its present status about its use in treating COVID-19 The COVID-19 disease has engulfed the entire world with...
There is no clarity on the natural origin of SARS CoV-2 as no intermediate host has been found yet that transmits it from bats to humans. On the other hand, there are circumstantial evidences to suggest a laboratory origin...
The assay time is considerably reduced from about an hour to few minutes by the newly reported RTF-EXPAR method which uses reverse transcriptase-free (RTF) approach for conversion of RNA into DNA followed by EXPAR (Exponential Amplification Reaction) for amplification at...
WHO has updated its living guidelines on COVID-19 therapeutics. The ninth update released on 03 March 2022 include a conditional recommendation on molnupiravir.  Molnupiravir has become the first oral antiviral drug to be included in the treatment guidelines for COVID-19....
MHRA, UK regulator has issued an advisory against the use of AstraZeneca vaccine as it has been shown to induce the formation of blood clots along with thrombocytopenia in rare cases (4 events in a million). However, in people...
A plasmid DNA vaccine against SARS-CoV-2 has been found to induce immunity in animal trials. Few other DNA based vaccine candidates are at early stages of clinical trials. Interestingly, plasmid DNA vaccines can be developed in a short period of time....
Existing biologics such as Canakinumab (monoclonal antibody), Anakinra (monoclonal antibody) and Rilonacept (fusion protein) can be exploited as therapeutics that restrain inflammation in COVID-19 patients. In addition, designer monoclonal antibodies can provide passive immunity by neutralizing the SARS-CoV-2 virus...
Cases of co-infections with two variants were earlier reported. Not much was known about viral recombination yielding viruses with hybrid genomes. Two recent studies report cases of genetic recombination among SARS-CoV-2 variants Denta & Omicron. The recombinant, called Deltamicron, had...
NeoCoV, a coronavirus strain related to MERS-CoV found in bats (NeoCoV is not a new variant of SARS-CoV-2, the human coronavirus strain responsible for COVID-19 pandemic) has been reported to be the first case of a MERS-CoV variant using ACE2....

FOLLOW US

101,274FansLike
75,477FollowersFollow
1,964FollowersFollow
31SubscribersSubscribe
- Advertisement -

RECENT POSTS