Cells with fully artificial synthesized genome were reported first in 2010 from which a minimalistic genome cell was derived that showed abnormal morphology upon cell division. Recent addition of a group of genes to this minimalistic cell...
MicroRNAs or in short miRNAs (not to be confused with mRNA or messenger RNA) were discovered in 1993 and have been extensively studied in the past two decades or so for their role in regulating gene expression....
Advanced age and comorbidities are known to be high risk factors for COVID-19. Does genetic make-up predispose some people making them more susceptible to severe symptoms? Conversely, does genetic make-up enable some people to have innate immunity...
The plant derived agent, Thapsigargin (TG) has been used in traditional medicine for long time. TG has shown promises as a potential anti-cancer drug because of its biological property to inhibit the sarcoplasmic/endoplasmic reticulum Ca2+ ATPase (SERCA) pump which is...
Brown fat is said to be “good". It is known that it plays an important role in thermogenesis and maintains body temperature when exposed to cold conditions. An increase in amount of BAT and/or its activation has...
Human Proteome Project (HPP) was launched in 2010 after successful completion of Human Genome Project (HGP) to identify, characterise and map human proteome (the entire set of proteins expressed by the human genome). On its tenth anniversary,...
A novel mechanism to explain the different unrelated symptoms of COVID-19 has come to light by exploiting the second fastest Supercomputer in the world known as Summit supercomputer at Oak Ridge National Lab...
Deletion of Phf21b gene is known to be associated with cancer and depression. New research now indicates that timely expression of this gene plays a key role in neural stem cell differentiation and brain development 
Coronaviruses are not new; these are as old as anything in the world and are known to cause common cold among humans for ages. However, its latest variant, the ‘SARS-CoV-2’ currently in news for causing COVID-19 pandemic...
Protein expression refers to the synthesis of proteins within cells using information contained in the DNA or gene.  Proteins are responsible for all the biochemical reactions that take place...
‘’The central dogma of molecular biology deals with the detailed residue-by-residue transfer of sequential information from DNA to protein via RNA. It states that such information is unidirectional from DNA to protein and cannot be transferred from...
‘Several questions about origin of life have been answered, but much remains to be studied’’ said Stanley Miller and Harold Urey way back in 1959 after reporting laboratory synthesis of amino acids in primitive earth conditions. Many...
The Human Genome Project revealed that ~1-2% of our genome makes functional proteins while the role of the remaining 98-99% remains enigmatic. Researchers have tried to uncover the mysteries surrounding the same and this article throws light...
Humans would not have existed without viruses because viral protein plays a key role in the development of human embryo. However, at times, they pose existential threats in the form of diseases as in the case of...
Researchers have adapted living cells and created novel living machines. Called xenobots, these are not a new species of animals but pure artefacts, designed to serve human needs in future.
Gingko trees lives for thousands years by evolving compensatory mechanisms to maintain a balance between growth and ageing. Ginkgo biloba, a deciduous gymnosperm tree native to China is known...
Success in mapping the complete neural network of male and female worms is an important progress towards understanding function of the nervous system. Our nervous system is an intricate...
Anorexia nervosa is an extreme eating disorder characterized with significant weight loss. Study on genetic origins of anorexia nervosa has revealed that metabolic differences play an equally important role along with psychological effects in the development of...
Scientists have demonstrated for the first time a multiple-person ‘brain-to-brain’ interface where three persons collaborated to complete a task via direct ‘brain-to-brain’ communication. This interface called BrainNet paves way for direct collaboration between brains for solving a problem.
Scientists have for the first time created an injectable hydrogel which beforehand incorporates tissue-specific bioactive molecules via novel crosslinkers. The hydrogel described has strong potential for usage in tissue engineering
This first case of genetic manipulation in a lizard has created a model organism that could help gain further understanding of reptile evolution and development CRISPR-Cas9 or simply CRISPR...
Scientists have revived pigs brain four hours after its death and kept alive outside the body for several hours Of all organs, brain is most susceptible to continuous supply...
New study in mice shows that getting enough sleep every night could provide protection from cardiovascular diseases Getting enough sleep is a general advice given by doctors as it...
Case study reports first rare semi-identical twins in humans to be identified during pregnancy and only second ever known till now Identical twins (monozygotic) are conceived when cells from...
Study shows for the first time healthy mouse offspring born from same sex parents – in this case mothers. The biological aspect of why mammals need two opposite genders...

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