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The complete human genome sequence of the two X chromosomes and autosomes from the female tissue derived cell line has been completed. This includes the 8% of the genome sequence that was missing in the original draft that was...
A recent 12 week trial comparing a normal carbohydrate-containing diet to the ketogenic diet in Alzheimer's Disease patients discovered that those who underwent a ketogenic diet increased their quality of life and activities of daily living outcomes, whilst also...
A new study reveals that bacterial DNA can be read either forwards or backwards due to the presence of symmetry in their DNA signals1. This finding challenges the existing knowledge about gene transcription, the mechanism by which the genes...
Androgens such as testosterone are generally viewed simplistically as creating aggression, impulsivity and antisocial behaviours. However, androgens influence behaviour in a complex way which includes promoting both pro- and antisocial behaviours, with a behavioural trend to increase social status1....
Nicotine has a vast array of neurophysiological effects, not all of which are negative despite popular opinion of nicotine as a simplistically harmful substance. Nicotine has various pro-cognitive effects and has even been used in transdermal therapy to improve...
Cells with fully artificial synthesized genome were reported first in 2010 from which a minimalistic genome cell was derived that showed abnormal morphology upon cell division. Recent addition of a group of genes to this minimalistic cell restored the...
MicroRNAs or in short miRNAs (not to be confused with mRNA or messenger RNA) were discovered in 1993 and have been extensively studied in the past two decades or so for their role in regulating gene expression. miRNAs are...
Advanced age and comorbidities are known to be high risk factors for COVID-19. Does genetic make-up predispose some people making them more susceptible to severe symptoms? Conversely, does genetic make-up enable some people to have innate immunity making them...
The plant derived agent, Thapsigargin (TG) has been used in traditional medicine for long time. TG has shown promises as a potential anti-cancer drug because of its biological property to inhibit the sarcoplasmic/endoplasmic reticulum Ca2+ ATPase (SERCA) pump which is necessary for...
Brown fat is said to be “good". It is known that it plays an important role in thermogenesis and maintains body temperature when exposed to cold conditions. An increase in amount of BAT and/or its activation has been shown...
Human Proteome Project (HPP) was launched in 2010 after successful completion of Human Genome Project (HGP) to identify, characterise and map human proteome (the entire set of proteins expressed by the human genome). On its tenth anniversary, HPP has...
A novel mechanism to explain the different unrelated symptoms of COVID-19 has come to light by exploiting the second fastest Supercomputer in the world known as Summit supercomputer at Oak Ridge National Lab in Tennessee. The study involved analysing 2.5...
Deletion of Phf21b gene is known to be associated with cancer and depression. New research now indicates that timely expression of this gene plays a key role in neural stem cell differentiation and brain development  A latest research published in...
Coronaviruses are not new; these are as old as anything in the world and are known to cause common cold among humans for ages. However, its latest variant, the ‘SARS-CoV-2’ currently in news for causing COVID-19 pandemic is new.   Often,...
Protein expression refers to the synthesis of proteins within cells using information contained in the DNA or gene.  Proteins are responsible for all the biochemical reactions that take place within the cell. Hence, it makes it necessary to study protein function in...
‘’The central dogma of molecular biology deals with the detailed residue-by-residue transfer of sequential information from DNA to protein via RNA. It states that such information is unidirectional from DNA to protein and cannot be transferred from protein to...
‘Several questions about origin of life have been answered, but much remains to be studied’’ said Stanley Miller and Harold Urey way back in 1959 after reporting laboratory synthesis of amino acids in primitive earth conditions. Many advances down...
The Human Genome Project revealed that ~1-2% of our genome makes functional proteins while the role of the remaining 98-99% remains enigmatic. Researchers have tried to uncover the mysteries surrounding the same and this article throws light on our...
Humans would not have existed without viruses because viral protein plays a key role in the development of human embryo. However, at times, they pose existential threats in the form of diseases as in the case of current COVID-19...
Researchers have adapted living cells and created novel living machines. Called xenobots, these are not a new species of animals but pure artefacts, designed to serve human needs in future. If biotechnology and genetic engineering were disciplines promising immense potential...
Gingko trees lives for thousands years by evolving compensatory mechanisms to maintain a balance between growth and ageing. Ginkgo biloba, a deciduous gymnosperm tree native to China is known commonly as health supplement and as herbal medicine. It is also known...
Success in mapping the complete neural network of male and female worms is an important progress towards understanding function of the nervous system. Our nervous system is an intricate connection of nerves and special cells called neurons which transmit signals...
Anorexia nervosa is an extreme eating disorder characterized with significant weight loss. Study on genetic origins of anorexia nervosa has revealed that metabolic differences play an equally important role along with psychological effects in the development of this disease....
Scientists have demonstrated for the first time a multiple-person ‘brain-to-brain’ interface where three persons collaborated to complete a task via direct ‘brain-to-brain’ communication. This interface called BrainNet paves way for direct collaboration between brains for solving a problem. A brain-to-brain interface in...
Scientists have for the first time created an injectable hydrogel which beforehand incorporates tissue-specific bioactive molecules via novel crosslinkers. The hydrogel described has strong potential for usage in tissue engineering Tissue engineering is the development of tissue and organ substitutes...

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