BIOLOGY

AI Designs Complete Functional Genomes

Umesh Prasad -
The genome language model Evo 2 has designed novel functional genomes of bacteriophage ΦX174. About 300 of the AI-generated designs were chemically synthesised and tested in...
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Chernobyl Fungi as Shield Against Cosmic Rays for Deep-Space Missions 

Umesh Prasad -
In 1986, the 4th unit of Chernobyl Nuclear Power Plant in Ukraine (erstwhile Soviet Union) suffered massive fire and steam explosion. The unprecedented accident released over 5% of the radioactive...
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Centromere sizes determine Unique Meiosis in Dogrose   

Umesh Prasad -
The dogrose (Rosa canina), the wild rose plant species, has a pentaploid genome with 35 chromosomes. It has an odd number of chromosomes, yet it...
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BIOLOGY

Cryptobiosis: Suspension of life over geological time scales has significance for evolution

Umesh Prasad -
Some organisms have ability to suspend life processes when under adverse environmental conditions. Called cryptobiosis or suspended animation, it is a survival tool. Organisms...
BIOLOGY

Craspase : a new safer “CRISPR – Cas System” that edits both Genes and Proteins  

Umesh Prasad -
“CRISPR-Cas systems” in bacteria and viruses identify and destroy invading viral sequences. It is bacterial and archaeal immune system for protection against viral infections. In...
BIOLOGY

Megatooth Sharks: Thermophysiology explains both its Evolution and Extinction

Umesh Prasad -
Extinct gigantic megatooth sharks were at the top of the marine food web once. Their evolution to gigantic sizes and their extinction are not...
BIOLOGY

Eukaryotes: Story of Its Archaeal Ancestry

Umesh Prasad -
The traditional grouping of life forms into prokaryotes and eukaryotes was revised in 1977 when rRNA sequence characterisation revealed that archaea (then called 'archaebacteria')...
BIOLOGY

Self-amplifying mRNAs (saRNAs): The Next Generation RNA Platform for Vaccines 

Umesh Prasad -
Unlike conventional mRNA vaccines which encodes only for the target antigens, the self-amplifying mRNAs (saRNAs) encodes for non-structural proteins and promotor as well which...
BIOLOGY

Would Synthetic Embryos Usher in the Era of Artificial Organs?   

Umesh Prasad -
Scientists have replicated the natural process of mammalian embryonic development in the laboratory up to the point of development of brain and heart. Using...
BIOLOGY

Discovery of a novel human protein that functions as RNA ligase: first report of such protein in higher eukaryotes 

Rajeev Soni -
RNA ligases play an important role in RNA repair, thereby maintaining RNA integrity. Any malfunction in RNA repair in humans seems to be associated...
BIOLOGY

Extinct Thylacine (Tasmanian tiger) to be Resurrected   

Umesh Prasad -
Ever changing environment leads to extinction of the animals unfit to survive in the changed environment and favours survival of the fittest which culminate in...
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BIOLOGY

AI Designs Complete Functional Genomes

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A Black Hole That Is Not Formed from Stellar Collapse 

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Meteor Produces Daytime Bolide and Sonic Boom Across New England  

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Carbon-free Ferrocene Analog Synthesised

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The synthesis of the first carbon-free inorganic sandwich compound  (an osmium...