A novel mechanism to explain the different unrelated symptoms of COVID-19 has come to light by exploiting the second fastest Supercomputer in the world known as Summit supercomputer at Oak Ridge National Lab...
There are reports of Russia registering world’s first vaccine against novel corona virus while the phase 3 trial of this vaccine is still in progress. Developed jointly by the Gamaleya Research Institute and the Russian Defence Ministry, this vaccine is based on...
Existing biologics such as Canakinumab (monoclonal antibody), Anakinra (monoclonal antibody) and Rilonacept (fusion protein) can be exploited as therapeutics that restrain inflammation in COVID-19 patients. In addition, designer monoclonal antibodies can provide passive immunity by neutralizing the...
Humans would not have existed without viruses because viral protein plays a key role in the development of human embryo. However, at times, they pose existential threats in the form of diseases as in the case of...
The infection fatality rate (IFR) is more reliable indicator of the extent of the infection. In this study, the researchers found the actual infection rate for COVID-19 in Heinsberg to be five-fold higher than the number officially...
Several new strains of the virus have emerged since the pandemic began. New variants were reported as early as February 2020. The current variant that has brought the UK to standstill this Christmas is said to be...
The novel coronavirus (2019-nCoV) has been given new name COVID-19 by the international body WHO which makes no reference to any of the people, places or animals associated with this virus.
Use of nasal gel as a novel means to inactivate COVID-19 in a biological manner and prevent its entry into human body may help avert community transmission of this virus, thereby helping in disease control and management.
Anti-viral properties of manuka honey are due to the presence of methylglyoxal (MG), an arginine directed glycating agent that modifies sites specifically present in the SARS-CoV-2 genome, thereby interfering with its replication and inhibiting the virus. In...
Viral proteins are administered as antigen in the form of a vaccine and the immune system of the body forms antibodies against the given antigen thus providing protection against any future infection. Interestingly, this is first time in...
Easily correctable condition of Vitamin D Insufficiency (VDI) has very severe implications for COVID-19. In countries worst affected by COVID-19 such as Italy, Spain and Greece, Vitamin D insufficiency (VDI) rates were high in the range of...
Laboratory tests for diagnosis of COVID-19 currently in practice as advised by the international bodies of experts are reviewed and evaluated. The COVID-19 disease, that originated in Wuhan China,...
Development of vaccine for COVID-19 is a global priority. In this article, the author has reviewed and evaluated research and development and the present status of vaccine development. COVID-19...
Low-cost dexamethasone reduces death by up to one third in hospitalised patients with severe respiratory complications of COVID-19 The scientists have been sceptic over the rationale for prolonged corticosteroid...
Several studies indicate that activation of NLRP3 inflammasome is responsible for acute respiratory distress syndrome and/or acute lung injury (ARDS/ALI) seen in severely ill COVID-19 patients which often result in death due to multiple organ failure. This...
A combination of biological and computational approach to study protein-protein interactions (PPIs) between the viral and the host proteins in order to identify and repurpose drugs for an effective treatment of COVID-19 and possibly other infections as...
University College London Hospitals (UCLH) has announced neutralising antibody trial against COVID-19. The announcement on 25 December 2020 says ‘’UCLH doses first patient in the world in Covid-19 antibody trial’’ and ‘’ Researchers in the STORM CHASER study...
For quicker lifting of lockdown, the innovators or entrepreneurs holding IP rights over novel technologies with potential to improve diagnostics and therapeutics for COVID-19, who may otherwise be unable to launch the products at scaled up level...
Social interaction and vaccination both contribute to development of herd immunity however development of herd immunity as a result of social interaction is directly proportional to the number of secondary infections that arise from the primary cases....
What causes severe COVID-19 symptoms? Evidences suggest inborn errors of type I Interferon immunity and autoantibodies against type I Interferon are causal for critical COVID-19. These errors can be identified using whole genome sequencing, thereby leading to...
The containment scheme based on 'quarantine' or 'social distancing' has emerged as the main tool in fight against COVID-19. But, there are concerns about economic and psychological costs. A researcher offers ''social containment'' as an alternative which...
WHO doesn't recommend face masks generally to the healthy people. However, CDC has now laid down new guideline and say ''people should wear cloth masks when they go outside''. New evidence suggest that the usage of surgical...
A type of virus that preys on bacteria could be harnessed to combat bacterial infections in patients whose immune systems have been weakened by the SARS-CoV-2 virus that causes the COVID-19 disease, according to an expert at...
Clinical Trials to evaluate effectiveness of anti-malarial drug, hydroxychloroquine (HCQ) and antibiotic, Azithromycin in treating older people with COVID-19 begins in the UK and USA with an aim to reducing the severity of symptoms and avoiding hospitalization
A plasmid DNA vaccine against SARS-CoV-2 has been found to induce immunity in animal trials. Few other DNA based vaccine candidates are at early stages of clinical trials. Interestingly, plasmid DNA vaccines can be developed in a short...

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