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The infection fatality rate (IFR) is more reliable indicator of the extent of the infection. In this study, the researchers found the actual infection rate for COVID-19 in Heinsberg to be five-fold higher than the number officially reported using...
Easily correctable condition of Vitamin D Insufficiency (VDI) has very severe implications for COVID-19. In countries worst affected by COVID-19 such as Italy, Spain and Greece, Vitamin D insufficiency (VDI) rates were high in the range of 70-90%.; on...
What causes severe COVID-19 symptoms? Evidences suggest inborn errors of type I Interferon immunity and autoantibodies against type I Interferon are causal for critical COVID-19. These errors can be identified using whole genome sequencing, thereby leading to proper quarantine...
Routine sero-surveillance of the population to estimate presence of antibodies to COVID-19 is required to understand the development of herd immunity in a population. Data from the sero-surveillance study of population in the Ischgl town of Austria throws light on this aspect...
There is no clarity on the natural origin of SARS CoV-2 as no intermediate host has been found yet that transmits it from bats to humans. On the other hand, there are circumstantial evidences to suggest a laboratory origin...
A plasmid DNA vaccine against SARS-CoV-2 has been found to induce immunity in animal trials. Few other DNA based vaccine candidates are at early stages of clinical trials. Interestingly, plasmid DNA vaccines can be developed in a short period of time....
Molnupiravir, a nucleoside analog of cytidine, a drug that has shown excellent oral bioavailability and promising results in Phase 1 and Phase 2 trials, could prove to be a magic bullet acting as an anti-viral agent against SARS-CoV2 in humans. Major...
The containment scheme based on 'quarantine' or 'social distancing' has emerged as the main tool in fight against COVID-19. But, there are concerns about economic and psychological costs. A researcher offers ''social containment'' as an alternative which seems to...
Laboratory tests for diagnosis of COVID-19 currently in practice as advised by the international bodies of experts are reviewed and evaluated. The COVID-19 disease, that originated in Wuhan China, has affected more than 208 countries till now. The scientific community...
The European Commission has launched www.Covid19DataPortal.org where the researchers can store and rapidly share datasets. The rapid sharing of relevant data would accelerate research and discovery. With an aim to support researchers by enabling rapid collection and sharing of available research data,...
Social interaction and vaccination both contribute to development of herd immunity however development of herd immunity as a result of social interaction is directly proportional to the number of secondary infections that arise from the primary cases. Herd immunity...
WHO doesn't recommend face masks generally to the healthy people. However, CDC has now laid down new guideline and say ''people should wear cloth masks when they go outside''. New evidence suggest that the usage of surgical face masks...
Several studies indicate that activation of NLRP3 inflammasome is responsible for acute respiratory distress syndrome and/or acute lung injury (ARDS/ALI) seen in severely ill COVID-19 patients which often result in death due to multiple organ failure. This suggests NLRP3...
The novel coronavirus (2019-nCoV) has been given new name COVID-19 by the international body WHO which makes no reference to any of the people, places or animals associated with this virus. The deadly novel coronavirus which has claimed thousands lives...
Convalescent plasma therapy holds key for the immediate treatment of severely sick COVID-19 patients. This article discusses effectiveness of this therapy and its present status about its use in treating COVID-19 The COVID-19 disease has engulfed the entire world with...
There are overwhelming evidences to confirm that the dominant route of transmission of severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) is airborne. This realisation has significant implications for fine-tuning of strategies to manage the pandemic, particularly in terms of importance...
A type of virus that preys on bacteria could be harnessed to combat bacterial infections in patients whose immune systems have been weakened by the SARS-CoV-2 virus that causes the COVID-19 disease, according to an expert at the University...
Clinical Trials to evaluate effectiveness of anti-malarial drug, hydroxychloroquine (HCQ) and antibiotic, Azithromycin in treating older people with COVID-19 begins in the UK and USA with an aim to reducing the severity of symptoms and avoiding hospitalization Of late, there...
In countries like UK, USA and Italy which are badly hit by the COVID-19 pandemic, the life expectancy has reduced by at least 1.2-1.3 years. Diseases and risk factors lead to premature deaths and disabilities and result in ‘burden’ on the...
The researchers at the Tel-Aviv Sourasky Medical Center have successfully completely Phase I trials for the use of CD24 protein delivered in exosomes to treat COVID-19. Scientists at the Tel-Aviv Sourasky Medical Center have devised a bio-therapeutic agent based on exosomes (membrane bound vesicles) carrying CD24 protein....
For quicker lifting of lockdown, the innovators or entrepreneurs holding IP rights over novel technologies with potential to improve diagnostics and therapeutics for COVID-19, who may otherwise be unable to launch the products at scaled up level due to...
The assay time is considerably reduced from about an hour to few minutes by the newly reported RTF-EXPAR method which uses reverse transcriptase-free (RTF) approach for conversion of RNA into DNA followed by EXPAR (Exponential Amplification Reaction) for amplification at...
Findings from recently concluded phase 2 clinical trials in Canada and the UK suggest nitric oxide (NO) could be very helpful in preventing and treating COVID-19. Nitric oxide NO, (not to be confused with nitrous oxide N2O used as anaesthetic in clinical...
Medicines and Healthcare products Regulatory Agency (MHRA), the regulator of all medicines and medical devices in the UK has approved Moderna’s COVID-19 vaccine after meeting the required safety, quality and effectiveness standards for use in the UK (1).   This is the...
COVID-19 pandemic has caused a major economic impact all over the globe and has resulted in disruption of “normal” life. Countries across the world are battling to find solutions to this disease that includes strengthening the immune system and...

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