Tag: Commentary

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COVID-19

2-Deoxy-D-Glucose(2-DG): A Potentially Suitable anti-COVID-19 drug

Umesh Prasad and Rajeev Soni -
2-Deoxy-D-Glucose(2-DG), a glucose analog that inhibits glycolysis, has recently received Emergency Use Authorization (EUA) in India for the treatment of moderate to severe COVID-19 patients....
COVID-19

CD24: an Anti-Inflammatory Agent for Treatment of COVID-19 Patients

Rajeev Soni -
The researchers at the Tel-Aviv Sourasky Medical Center have successfully completely Phase I trials for the use of CD24 protein delivered in exosomes to treat COVID-19. Scientists at...
HEALTH

Negative Effect of Fructose on the Immune System

Neelesh Prasad -
New study suggests that increased dietary intake of fructose (fruit sugar) may have negative effect on immunity. This further adds reason to caution dietary...
HEALTH

Potential Use for New GABA-Targeting Drugs in Alcohol Use Disorder

Neelesh Prasad -
Use of GABAB (GABA type B) agonist, ADX71441, in preclinical trials caused significant reductions in alcohol intake. The drug potently reduced motivation to drink and...
ARCHAEOLOGICAL SCIENCE

The Genetic Ancestors and Descendants of the Indus Valley Civilisation

Neelesh Prasad -
The Harappan Civilisation was not a combination of recently immigrated Central Asians, Iranians or Mesopotamians which imported civilizational knowledge, but instead was a distinct...
HEALTH

IGF-1: Trade Off Between Cognitive Function and Cancer Risk

Neelesh Prasad -
Insulin-like growth factor 1 (IGF-1) is a prominent growth factor which conducts many of the growth-promoting effects of growth hormone (GH) through GH's stimulation...
HEALTH

Intermittent Fasting or Time-Restricted Feeding (TRF) Has Significant Negative Effects on Hormones

Neelesh Prasad -
Intermittent fasting has a wide range of effects on the endocrine system of which many could be detrimental. Therefore, time-restricted feeding (TRF) should not...
MEDICINE

Donepezil’s Effects on Brain Regions

Neelesh Prasad -
Donepezil is an acetylcholinesterase inhibitor1. Acetylcholinesterase breaks down the neurotransmitter acetylcholine2, thereby reducing acetylcholine signalling in the brain. Acetylcholine (ACh) enhances the encoding of...
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