Neelesh Prasad

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HEALTH

IGF-1: Trade Off Between Cognitive Function and Cancer Risk

Neelesh Prasad -
Insulin-like growth factor 1 (IGF-1) is a prominent growth factor which conducts many of the growth-promoting effects of growth hormone (GH) through GH's stimulation...
HEALTH

Intermittent Fasting or Time-Restricted Feeding (TRF) Has Significant Negative Effects on Hormones

Neelesh Prasad -
Intermittent fasting has a wide range of effects on the endocrine system of which many could be detrimental. Therefore, time-restricted feeding (TRF) should not...
MEDICINE

Donepezil’s Effects on Brain Regions

Neelesh Prasad -
Donepezil is an acetylcholinesterase inhibitor1. Acetylcholinesterase breaks down the neurotransmitter acetylcholine2, thereby reducing acetylcholine signalling in the brain. Acetylcholine (ACh) enhances the encoding of...
MEDICINE

Selegiline’s Wide Array of Potential Therapeutic Effects

Neelesh Prasad -
Selegiline is an irreversible monoamine oxidase (MAO) B inhibitor1. Monoamine neurotransmitters, such as serotonin, dopamine and norepinephrine, are derivatives of amino acids2. The enzyme...
HEALTH

Hypertrophic Effect of Endurance Exercise and the Potential Mechanisms

Neelesh Prasad -
Endurance, or "aerobic" exercise, is generally viewed as cardiovascular exercise and is not generally associated with skeletal muscle hypertrophy. Endurance exercise is defined as...
BIOLOGY

Potential Therapeutic Role of Ketones in Alzheimer’s Disease

Neelesh Prasad -
A recent 12 week trial comparing a normal carbohydrate-containing diet to the ketogenic diet in Alzheimer's Disease patients discovered that those who underwent a...
BIOLOGY

Effects of Androgens on the Brain

Neelesh Prasad -
Androgens such as testosterone are generally viewed simplistically as creating aggression, impulsivity and antisocial behaviours. However, androgens influence behaviour in a complex way which...
BIOLOGY

Nicotine’s Varying (Positive and Negative) Effects on the Brain

Neelesh Prasad -
Nicotine has a vast array of neurophysiological effects, not all of which are negative despite popular opinion of nicotine as a simplistically harmful substance....
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