Most Recent Articles by

Rajeev Soni

Dr. Rajeev Soni (ORCID ID : 0000-0001-7126-5864) has a Ph.D. in Biotechnology from the University of Cambridge, UK and has 25 years of experience working across the globe in various institutes and multinationals such as The Scripps Research Institute, Novartis, Novozymes, Ranbaxy, Biocon, Biomerieux and as a principal investigator with US Naval Research Lab in drug discovery, molecular diagnostics, protein expression, biologic manufacturing and business development.

57 Articles written

BIOLOGY

Cells with Synthetic Minimalistic Genome Undergo Normal Cell Division

Cells with fully artificial synthesized genome were reported first in 2010 from which a minimalistic genome cell was derived that showed abnormal morphology upon...

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COVID-19

Nasal Spray Vaccine for COVID-19

All approved COVID-19 vaccines so far are administered in the form of injections. What if the vaccines could be conveniently delivered as spray in...

Rajeev Soni -

COVID-19

Ischgl Study: Development of Herd Immunity and Vaccine Strategy against COVID-19

Routine sero-surveillance of the population to estimate presence of antibodies to COVID-19 is required to understand the development of herd immunity in a population....

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COVID-19

microRNAs: New Understanding of Mechanism of Action in Viral Infections and its Significance

MicroRNAs or in short miRNAs (not to be confused with mRNA or messenger RNA) were discovered in 1993 and have been extensively studied in...

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COVID-19

Could Polymersomes be better Delivery vehicle for COVID Vaccines?

A number of ingredients have been used as carriers to successfully deliver vaccines and to enhance their immune response. These include peptides, liposomes, lipid...

Rajeev Soni -

COVID-19

COVID-19: Use of Hyperbaric Oxygen Therapy (HBOT) in Treatment of Severe Cases

COVID-19 pandemic has caused a major economic impact all over the globe and has resulted in disruption of “normal” life. Countries across the world...

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BIOLOGY

The Science of Brown Fat: What more is Yet to be Known?

Brown fat is said to be “good". It is known that it plays an important role in thermogenesis and maintains body temperature when exposed...

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COVID-19

COVID-19, Immunity & Honey: Recent Advances in Understanding Medicinal Properties of Manuka Honey

Anti-viral properties of manuka honey are due to the presence of methylglyoxal (MG), an arginine directed glycating agent that modifies sites specifically present in...

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COVID-19

‘Bradykinin Hypothesis’ Explains the Exaggerated Inflammatory Response in COVID-19

A novel mechanism to explain the different unrelated symptoms of COVID-19 has come to light by exploiting the second fastest Supercomputer in the world...

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ENGINEERING & TECHNOLOGY

Neuralink: A Next Gen Neural Interface That Could Change Human Lives

Neuralink is an implantable device that has shown significant improvement over others in that it supports flexible cellophane-like conductive wires inserted into the tissue using...

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BIOLOGY

PHF21B Gene Implicated in Cancer Formation and Depression has a Role in Brain Development too

Deletion of Phf21b gene is known to be associated with cancer and depression. New research now indicates that timely expression of this gene plays...

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MEDICINE

Aviptadil Could Reduce Mortality Among Severely Ill COVID Patients

In June 2020, RECOVERY trial from a group of researchers in Oxford University UK reported use of low-cost dexamethasone1 for treatment of severely ill COVID-19...

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BIOLOGY

Story of Coronaviruses: How the ‘’novel Coronavirus (SARS-CoV-2)’’ May Have Emerged?

Coronaviruses are not new; these are as old as anything in the world and are known to cause common cold among humans for ages....

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COVID-19

Monoclonal Antibodies and Protein Based Drugs Could be Used to Treat COVID-19 Patients

Existing biologics such as Canakinumab (monoclonal antibody), Anakinra (monoclonal antibody) and Rilonacept (fusion protein) can be exploited as therapeutics that restrain inflammation in COVID-19...

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COVID-19

Dexamethasone: Have Scientists Found Cure for Severely Ill COVID-19 Patients?

Low-cost dexamethasone reduces death by up to one third in hospitalised patients with severe respiratory complications of COVID-19 The scientists have been sceptic over the...

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BIOLOGY

‘Central Dogma of Molecular Biology’: Should ‘Dogmas’ and ‘Cult Figures’ Have Any Place in Science?

‘’The central dogma of molecular biology deals with the detailed residue-by-residue transfer of sequential information from DNA to protein via RNA. It states that...

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BIOLOGY

Molecular Origin of Life: What Formed First – Protein, DNA or RNA or a Combination Thereof?

‘Several questions about origin of life have been answered, but much remains to be studied’’ said Stanley Miller and Harold Urey way back in...

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COVID-19

Vitamin D Insufficiency (VDI) Leads to Severe COVID-19 Symptoms

Easily correctable condition of Vitamin D Insufficiency (VDI) has very severe implications for COVID-19. In countries worst affected by COVID-19 such as Italy, Spain...

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BIOLOGY

How the Mysterious ‘Dark Matter’ Regions of Human Genome Influence Our Health?

The Human Genome Project revealed that ~1-2% of our genome makes functional proteins while the role of the remaining 98-99% remains enigmatic. Researchers have...

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SCIENCE POLICY

Bridging the Gap Between Science and The Common Man: A Scientist’s Perspective

The hard work performed by the scientists lead to limited success, which is measured by peers and contemporaries by way of publications, patents and...

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COVID-19

NLRP3 Inflammasome: A Novel Drug Target for Treating Severely Ill COVID-19 Patients

Several studies indicate that activation of NLRP3 inflammasome is responsible for acute respiratory distress syndrome and/or acute lung injury (ARDS/ALI) seen in severely ill...

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COVID-19

Humans and Viruses: A Brief History of Their Complex Relationship And Implications for COVID-19

Humans would not have existed without viruses because viral protein plays a key role in the development of human embryo. However, at times, they...

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COVID-19

A Novel Approach to ‘Repurpose’ Existing Drugs For COVID-19

A combination of biological and computational approach to study protein-protein interactions (PPIs) between the viral and the host proteins in order to identify and...

Rajeev Soni -

COVID-19

Development of Herd Immunity against COVID-19: When Do We Know That an Adequate Level is Reached to Lift Lockdown?

Social interaction and vaccination both contribute to development of herd immunity however development of herd immunity as a result of social interaction is directly...

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COVID-19

ISARIC Study Indicates How Social Distancing Could Be Fine-tuned in Near Future to Optimise ‘Protecting Lives’ and ‘Kickstart National Economy’

The recently completed UK-wide, ISARIC Study on analysis of 16749 patients with severe COVID-19 disease across 166 hospitals indicated that those with co-morbidity were...

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