Omega-3 Supplements May Not Offer Benefit to The Heart

An elaborate comprehensive study shows Omega-3 supplements may not offer benefit to the heart

It is believed that small portions of omega-3 – a type of fat – can be good for one’s health. Alphalinolenic acid (ALA), eicosapentaenoic acid (EPA), and docosahexaenoic acid (DHA) are the three main types of omega-3 fatty acids. These can be naturally found in foods which we eat daily example plant foods like nuts and seeds contain ALA and fatty fish like salmon or tuna and fish oils contain EPA and DHA. It is a widely accepted and popular belief or rather a ‘fact’ based upon some early clinical trials in 1980s and 1990s that consuming omega-3 fats can provide protection against heart related diseases like heart attack, stroke or death by lowering blood pressure or reducing cholesterol levels. Omega-3 supplements in the form of capsules are available over-the-counter and are consumed by many people on a daily basis with or without a doctor’s prescription.

Meta-analysis – a combination of many trials

A recent Cochrane systematic review shows that omega-3 supplements have very slight or no effect on one’s risk of heart diseases based upon a comprehensive review of evidence. Cochrane organisation is a global network of experts dedicated to informing health policy. For this study, a total of 79 randomized trials were conducted with 112,059 people to evaluate the effects of taking omega-3 fat on heart circulation and diseases. 25 studies were designed and conducted and participants were from North America, Australia, Europe and Asia. Both men and women either healthy or having minor or major illnesses were included as participants. Randomly chosen, each participant had to either maintain their diet or along with diet take omega-3 fat supplement in the form of a daily capsule for one year. The meta-analysis assessed daily intake of omega-3 fat and few studies assessed intake of oily fish like salmon and tuna or ALA-rich foods while other participants were asked to maintain usual intake of food.

Omega-3 supplements have no considerable effect

Researchers concluded after evaluating the outcomes that there was evidence of high certainty that omega-3 had slight or no impact on a person’s risk of heart attacks, strokes or heart irregularities. Also, omega-3 has ‘no considerable effect’ on risk of death as it was calculated at 8.8% for participants who took supplements, while 9% for controlled group who took normal food and did not take supplements. Omega 3 supplements had no effect on risk of cardiovascular events like stroke etc. EPA and DHA- the long chain omega-3 fatty acids – reduced some blood fat, triglycerides (which could be indicative of protection from heart diseases) and HDL cholesterol but then reducing HDL had an opposite effect.

There was ‘moderate evidence’ that consuming more ALA from supplemented walnuts may have small benefit on risk of main cardiovascular events or body weight seeing that risk of irregularities in the heart was reduced from 3.3 to 2.6 %. Consumption of canola oil and nuts was seen of a small benefit especially in preventing heart arrhythmias. No evidence was collected on benefits of eating more oily fish and not much information could be collected on adverse scenarios like bleeding or blood clots from ALA. From extensive information collected from the 25 studies, no clear-cut protective effects of omega-3 were seen. The overall chance of receiving any benefits from omega-3 supplements was stated as one in 1,000.

Healthy diet is more important

The popular and widely accepted belief that EPA and DHA omega-3 supplements protect the heart has been cited as controversial and is still debatable. Many experts believe that it is anyway very unlikely that one particular element of diet could be alone responsible for reducing risk of heart diseases. The financial aspect of consuming supplements is also side-lined and it would rather be recommended to have an overall healthy diet and stop unnecessary use of over-the-counter supplements. However, if omega-3 supplements have been advised by the doctor for some specific reason then one must continue their intake. Otherwise the best recommendation to get omega-3 through natural foods rather than supplements

This meta-analysis is seen as a dependable comprehensive systematic review which has collected information spanned over long time durations from large groups of people providing strong evidences and has concluded that increasing intake of omega-3 fats may not be protective of our hearts. Only ALA which is actually an essential fatty acid, is said to be an important part of a balanced diet and its increased intake can be somewhat useful for preventing and maybe treating cardiovascular events. This review conducted by Cochrane organisation was requested by World Health Organization who are in the process of updating their guidelines on polyunsaturated fats.


{You may read the original research paper by clicking the DOI link given below in the list of cited source(s)}


Abdelhamid AS et al. 2018. Omega‐3 fatty acids for the primary and secondary prevention of cardiovascular disease. Cochrane Database of Systematic Reviews


Scientific European® | | Significant advances in science. Impact on humankind. Inspiring minds.

Subscribe to our newsletter

To be updated with all the latest news, offers and special announcements.

Most Popular Articles

The upper part of the statue of Ramesses II uncovered 

A team of researchers led by Basem Gehad of...

‘Ionic Wind’ Powered Airplane: A Plane That Has No Moving Part

Airplane has been designed which won’t be dependent on...

50% of type 2 diabetics in 16 to 44 years age group in England...

Analysis of Health Survey for England 2013 to 2019...
- Advertisement -