MEDICINE

Outbreak of Bundibugyo Ebolavirus in DR Congo and Uganda

Umesh Prasad -
The current orthoebolavirus outbreak in Democratic Republic of Congo (DRC) and Uganda is confirmed to be caused by the species Orthoebolavirus bundibugyoense (Bundibugyo virus),...
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Tumour Treating Fields (TTFields) approved for Pancreatic cancer

Umesh Prasad -
Cancer cells have electrically charged parts hence are influenced by electric fields. Application of alternating electric fields (TTFields) to solid tumours selectively target and...
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Two Novel Henipaviruses Detected in Fruit bats in China 

Umesh Prasad -
The henipaviruses, Hendra virus (HeV) and Nipah virus (NiV) are known to cause fatal diseases in humans. In 2022, Langya henipavirus (LayV), a novel henipavirus was identified in Eastern...
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MEDICINE

HIV/AIDS: mRNA Vaccine Shows Promise in Pre-clinical Trial  

SCIEU Team -
Successful development of mRNA vaccines, BNT162b2 (of Pfizer/BioNTech) and mRNA-1273 (of Moderna) against the novel coronavirus SARS CoV-2 and the important role these vaccines...
MEDICINE

RNA Technology: from Vaccines against COVID-19 to Treatment of Charcot-Marie-Tooth disease

SCIEU Team -
RNA technology has proved its worth recently in development of mRNA vaccines BNT162b2 (of Pfizer/BioNTech) and mRNA-1273 (of Moderna) against COVID-19. Based on degrading...
MEDICINE

First Successful Transplant of Heart of a Genetically-modified (GM) Pig into Human

SCIEU Team -
Doctors and scientists of University of Maryland School of Medicine have successfully transplanted heart of a genetically engineered pig (GEP) into an adult patient...
MEDICINE

Spinal Cord Injury (SCI): Exploiting Bio-active Scaffolds to Restore Function

Rajeev Soni -
Self-assembled nanostructures formed using supramolecular polymers containing peptide amphiphiles (PAs) containing bio active sequences have shown great results in mouse model of SCI and holds immense promise, in...
MEDICINE

Iboxamycin (IBX): a Synthetic Broad-Spectrum Antibiotic to address Anti-Microbial Resistance (AMR)

Umesh Prasad -
Development of multi-drug resistance (MDR) bacteria in the past five decades have led to increasing research in search of a drug candidate to address this AMR...
MEDICINE

Anti-Malaria Vaccines: Will New Found DNA Vaccine Technology Influence Future Course?

Rajeev Soni -
Developing vaccine against malaria has been among the biggest challenges before science. MosquirixTM , a vaccine against malaria has recently been approved by WHO. Although the...
MEDICINE

Donepezil’s Effects on Brain Regions

Neelesh Prasad -
Donepezil is an acetylcholinesterase inhibitor1. Acetylcholinesterase breaks down the neurotransmitter acetylcholine2, thereby reducing acetylcholine signalling in the brain. Acetylcholine (ACh) enhances the encoding of...
MEDICINE

Selegiline’s Wide Array of Potential Therapeutic Effects

Neelesh Prasad -
Selegiline is an irreversible monoamine oxidase (MAO) B inhibitor1. Monoamine neurotransmitters, such as serotonin, dopamine and norepinephrine, are derivatives of amino acids2. The enzyme...
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